National Path Lab

Autoimmune & Rheumatology

Autoimmune and rheumatic diseases occur when the immune system reacts abnormally against the body's own cells, tissues or organs. These conditions can affect the joints, muscles, skin, blood vessels, kidneys, nervous system and other organs.

Symptoms such as persistent joint pain, swelling, morning stiffness, unexplained fatigue, recurrent fever, skin rashes, dry eyes or mouth, recurrent blood clots or certain neurological symptoms may require evaluation for an autoimmune or inflammatory condition.

Laboratory tests can help doctors identify autoantibodies, inflammation, immune-system abnormalities and evidence of organ involvement. At National Path Lab (NPL), specialized laboratory investigations are available to support the evaluation and monitoring of selected autoimmune and rheumatological conditions.

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Conditions (8)

About Autoimmune & Rheumatology

Conditions Covered on This Page

  • Rheumatoid Arthritis (RA)

  • Systemic Lupus Erythematosus (SLE)

  • Sjögren Syndrome

  • Vasculitis

  • Antiphospholipid Syndrome (APS)

  • Demyelinating Disease

  • Autoimmune Hepatitis

Why Is Autoimmune Testing Sometimes Done as a Combination?

Autoimmune diseases can have overlapping symptoms. For example, joint pain can occur in rheumatoid arthritis, lupus, Sjögren syndrome and other inflammatory conditions. Clinicians may therefore combine disease-specific antibodies, general inflammatory markers, and organ-function tests to build a clearer clinical picture.

However, more tests do not always mean better diagnosis. Broad autoimmune testing without an appropriate clinical indication may produce incidental positive results that can be difficult to interpret. Targeted testing based on clinical suspicion is generally more useful.

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