National Path Lab
Infectious Disease & Molecular Testing

Tuberculosis

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Laboratory diagnosis may involve microbiological, molecular, and microscopic approaches depending on the clinical presentation and specimen available.

Rapid molecular testing can be particularly useful when tuberculosis is clinically suspected and timely treatment decisions are important, since molecular assays can detect the organism and, depending on the assay, provide information about selected drug-resistance markers.

At National Path Lab (NPL), comprehensive tuberculosis diagnostic testing is available, including AFB smear, mycobacterial culture, molecular testing, and drug-resistance testing.

Tests available
5
Tests available
Health package
1
Health package

Tests Available at NPL

AFB STAIN, SPUTUM

Turn Around Time
SAMPLE DAILY BY 7:00 PM REPORT ON NEXT DAY EVENING

Rs. 300

MYCOBACTERIUM TB PCR

Turn Around Time
SAMPLE BY MON/WED/FRI 8:00 AM REPORT ON SAME DAY LATE EVENING

Rs. 3600

QUANTIFERON®-TB GOLD (QFT)/TB-IGRA (INTERFERON GAMMA RELEASE ASSAY)

Turn Around Time
SAMPLE BY SAT TO THU 3:00 PM REPORT ON NEXT DAY LATE EVENING

Rs. 5000

GENEXPERT MTB PCR WITH RIFAMPICIN RESISTANCE

Turn Around Time
SAMPLE DAILY BY 7:00 PM REPORT AFTER 7 DAYS

Rs. 4600

CULTURE AFB MYCOBACTERIUM

Turn Around Time
SAMPLE DAILY BY 12:00 PM, REPORT AFTER 6 WEEKS.

Rs. 2500

About Tuberculosis

diagnostic pathway.

Because TB treatment is prolonged and drug resistance has serious public health implications, drug-resistance testing is an important complement to organism detection, helping ensure the correct treatment regimen is selected from the outset where resistance testing is performed.

In practice, these investigations are often used together rather than as alternatives — a rapid molecular result can guide immediate treatment decisions while culture confirms the diagnosis and, where needed, provides more detailed drug-susceptibility information.

Tests Available at NPL

Test Code

Test

Clinical Relevance

M0013

AFB Smear

A rapid microscopic test that can provide an initial indication of mycobacteria, though with lower sensitivity than culture or molecular testing.

OS072

Mycobacterial Culture

The gold-standard confirmatory test, though it can take several weeks to yield results due to the slow growth of the organism.

N0009

MYCOBACTERIUM TB PCR

Detects Mycobacterium tuberculosis complex genetic material, providing faster results than culture.

I0129

QUANTIFERON®-TB GOLD (QFT)/TB-IGRA

(INTERFERON GAMMA RELEASE ASSAY)

 

OS099

GENEXPERT MTB PCR WITH RIFAMPICIN

RESISTANC

 

Most infectious-disease molecular tests and microbiological investigations do not require fasting. However, some blood tests ordered at the same time may have specific preparation requirements. Please follow the instructions provided by your doctor or NPL.

Home Sample Collection

Sputum sample collection for TB testing can, in many cases, be arranged through NPL's home sample collection service — our team will provide a proper collection container and instructions for producing an adequate sputum sample.

In some cases, your doctor may request the sample be collected under supervision at a clinic to ensure sample adequacy, particularly if a home-collected sample is inadequate.

Blood samples for accompanying tests can also be collected at home.

Reports are delivered securely to your treating doctor and to you, with turnaround time depending on the specific test — culture results take considerably longer than smear or molecular testing.

 

When to See a Doctor

•  Cough lasting more than 2–3 weeks

•  Coughing up blood, at any point

•  Unexplained fever, night sweats, or weight loss

•  Known close contact with a person with active TB

•  Known TB with new or worsening symptoms despite treatment

Medical Disclaimer

Laboratory tests support tuberculosis diagnosis but must be interpreted by a qualified doctor together with clinical presentation, chest imaging, and exposure history. This content is for general information only and is not a substitute for medical advice, diagnosis, or treatment.

Related Packages

BASIC STI PROFILE

Test Includes
11 Tests

Rs. 8800

Frequently Asked Questions

Mycobacterium tuberculosis grows slowly compared to most bacteria, so culture-based confirmation can take several weeks, even though it remains an important gold-standard test.
No. TB diagnosis typically relies on sputum-based testing (smear, molecular, or culture), sometimes combined with imaging and clinical assessment, rather than a blood test alone.
No, sputum-based and blood-based TB testing does not require fasting.
It means the TB bacteria are resistant to one or more standard anti-TB medications, requiring a modified treatment regimen. Drug-resistance testing helps identify this so appropriate treatment can be selected.
This depends on the specific test and your doctor's protocol; your care team will advise on the number and timing of samples needed for accurate results.