Total IgE & Allergy Evaluation
Total IgE measures the overall concentration of immunoglobulin E in the blood. IgE plays an important role in allergic reactions, and elevated levels can occur in atopic diseases, allergic conditions, certain parasitic infections, and some immunological disorders.
Total IgE is not a specific test for allergy. Specific-IgE testing and clinical history may provide more useful information when a particular allergen is suspected.
At National Path Lab (NPL), total IgE testing is available, typically used alongside specific-IgE testing and clinical assessment for a more complete allergy evaluation.
- Test available
- 1
- Test available
- Health package
- 1
- Health package
Tests Available at NPL
IMMUNOGLOBULIN IGE
SAMPLE DAILY BY 7:00 PM REPORT ON SAME DAY
Rs. 1800
About Total IgE & Allergy Evaluation
Causes & Risk Factors
Total IgE testing is considered as a component of broader allergy or immune evaluation, rather than in response to specific risk factors:
• Suspected atopic disease (eczema, asthma, allergic rhinitis) where overall IgE level may provide supportive information.
• Unexplained allergic-type symptoms where a broader immune picture is helpful.
• Suspected parasitic infection, which can also elevate total IgE.
• Monitoring of certain atopic conditions over time, in specific clinical contexts.
• As part of a broader immunological work-up when other immune disorders are being considered.
Symptoms & When to Test
Total IgE testing is not directly tied to a specific symptom, since it is a general marker rather than an allergen-specific test.
• Considered alongside symptoms of atopic disease — eczema, asthma, allergic rhinitis
• May be tested when allergy symptoms are present but the specific trigger is unclear
• Used as part of a broader work-up rather than as a stand-alone diagnostic symptom-driven test
When Should You Consider Testing?
Total IgE is generally tested as part of a broader allergy or immune evaluation, alongside specific-IgE testing and clinical history, rather than as a stand-alone test for a specific symptom.
Why Tests Are Combined
Because total IgE can be elevated in many different conditions — atopic disease, parasitic infection, certain immune disorders — an elevated result alone does not identify the cause, which is why it is generally interpreted alongside specific-IgE testing (which identifies the specific allergen) and clinical history.
A normal total IgE does not exclude allergy, and an elevated total IgE does not confirm allergy — this is why total IgE functions best as a supportive, contextual piece of information rather than a stand-alone diagnostic test.
In practice, doctors often order total IgE together with a relevant specific-IgE panel, using the total IgE as background context for interpreting the more targeted specific-IgE results.
Tests Available at NPL
Test Code | Test | Clinical Relevance |
B0094
| Total IgE | Measures overall immunoglobulin E concentration in blood; used as supportive information alongside specific-IgE testing and clinical history. |
Most allergy and immunology blood tests do not require fasting. However, some tests ordered at the same time may have specific preparation requirements. Please follow the instructions provided by your doctor or NPL.
Home Sample Collection
NPL offers convenient home sample collection for Total IgE & Allergy Evaluation blood tests, so you don't need to visit a lab in person.
→ Book your test online, via the NPL app, or by calling +977 1 5970147 and select a convenient time slot for home sample collection.
→ A certified and experienced NPL phlebotomist visits your home at the scheduled time, following strict hygiene and safety protocols.
→ Your sample is transported under controlled, monitored conditions to NPL's NABL ACCREDITED UNDER ISO15189:2012laboratory for processing.
→ Your digital report is delivered securely to your phone or email, along with access to download and share it as needed.
When to See a Doctor
• Chronic or unexplained allergic-type symptoms
• Known atopic disease (eczema, asthma, allergic rhinitis) requiring evaluation
• Unexplained elevated IgE found on prior testing
• As part of a broader immune evaluation recommended by your doctor
Medical Disclaimer Total IgE testing supports allergy and immune evaluation but is not a specific or stand-alone diagnostic test. Results must be interpreted by a qualified doctor together with clinical history and, where relevant, specific-IgE testing. This content is for general information only and is not a substitute for medical advice, diagnosis, or treatment. |